๐ก๐ก๐ก ๐๐ซ.๐๐๐๐๐ฏ ๐๐ง๐ ๐๐ซ.๐๐จ๐ฌ๐๐ฉ๐ก ๐ฅ๐จ๐จ๐ค ๐ญ๐จ ๐ฌ๐๐ญ๐ญ๐ฅ๐ ๐ญ๐ก๐ ๐๐๐๐๐ญ๐ ๐ข๐ง ๐๐๐๐ ๐๐ ๐จ๐ ๐ฐ๐ป ๐ป๐จ๐ฒ๐ฌ๐บ 2 ๐ป๐ถ ๐ป๐๐ฒ 2. ๐ข๐๐๐ฏ๐ ๐ฒ๐จ๐ฎ ๐๐๐๐ง ๐ฐ๐จ๐ง๐๐๐ซ๐ข๐ง๐ ๐ฐ๐ก๐๐ญ'๐ฌ ๐ญ๐ก๐ ๐ซ๐๐๐ฅ ๐๐ข๐๐๐๐ซ๐๐ง๐๐ ๐๐๐ญ๐ฐ๐๐๐ง #๐๐๐ ๐ข๐ง๐ก๐ข๐๐ข๐ญ๐ข๐จ๐ง ๐๐ง๐ #๐๐๐-๐ ๐ข๐ง๐ก๐ข๐๐ข๐ญ๐ข๐จ๐ง? ๐๐ซ๐๐ง'๐ญ ๐ญ๐ก๐๐ฒ ๐ฉ๐๐ซ๐ญ ๐จ๐ ๐ญ๐ก๐ ๐ฌ๐๐ฆ๐ ๐ฉ๐๐ญ๐ก๐ฐ๐๐ฒ? ๐ช๐ฒ๐น๐น ๐๐ฒ ๐๐ฎ๐ธ๐ฒ ๐ฎ ๐ฑ๐ฒ๐ฒ๐ฝ ๐ฑ๐ถ๐๐ฒ ๐ถ๐ป๐๐ผ ๐๐ต๐ฒ ๐๐ฎ๐ณ๐ฒ๐๐ ๐ฐ๐ผ๐ป๐๐ฒ๐ฟ๐๐ฎ๐๐ถ๐ผ๐ป ๐ฎ๐ป๐ฑ seek clarify for you when it comes to all you need to know about key ๐ง๐ฌ๐ ๐๐ ๐๐๐ ๐๐ถ๐ฑ๐ฒ ๐ฒ๐ณ๐ณ๐ฒ๐ฐ๐ ๐ฎ๐ป๐ฑ ๐บ๐ผ๐ป๐ถ๐๐ผ๐ฟ๐ถ๐ป๐ด ๐ฐ๐ผ๐ป๐๐ถ๐ฑ๐ฒ๐ฟ๐ฎ๐๐ถ๐ผ๐ป๐. Our experts ๐ฎ๐น๐๐ผ ๐ฏ๐ฟ๐ฒ๐ฎ๐ธ๐ฑ๐ผ๐๐ป ๐ฃ๐ข๐๐ง๐ฌ๐-๐ญ ๐ฎ๐ป๐ฑ ๐ฃ๐ข๐๐ง๐ฌ๐-๐ฎ ๐ฎ๐ป๐ฑ ๐๐ต๐ฎ๐ฟ๐ฒ ๐๐ต๐ฒ๐ถ๐ฟ ๐ฐ๐ฎ๐ป๐ฑ๐ถ๐ฑ ๐๐ต๐ผ๐๐ด๐ต๐๐ ๐ผ๐ป ๐๐ต๐ฒ๐ฟ๐ฒ ๐๐ต๐ฒ๐ ๐๐ฒ๐ฒ ๐๐ต๐ฒ ๐ฝ๐น๐ฎ๐ฐ๐ฒ ๐ผ๐ณ ๐ฎ ๐ง๐ฌ๐-๐ฎ ๐ถ๐ป๐ต๐ถ๐ฏ๐ถ๐๐ผ๐ฟ, ๐ถ๐ป ๐๐ต๐ฒ๐ถ๐ฟ ๐ฝ๐ฟ๐ฎ๐ฐ๐๐ถ๐ฐ๐ฒ๐, ๐ณ๐ผ๐ฟ ๐๐ต๐ฒ ๐๐ฟ๐ฒ๐ฎ๐๐บ๐ฒ๐ป๐ ๐ผ๐ณ ๐บ๐ผ๐ฑ๐ฒ๐ฟ๐ฎ๐๐ฒ ๐๐ผ ๐๐ฒ๐๐ฒ๐ฟ๐ฒ ๐ฝ๐๐ผ๐ฟ๐ถ๐ฎ๐๐ถ๐. ๐ข๐ผ๐ง๐ ๐ฉ๐๐๐ง๐ ๐๐ฃ๐ฎ ๐ฅ๐ง๐๐๐ฉ๐๐๐๐ก ๐๐ค๐ฃ๐จ๐๐๐๐ง๐๐ฉ๐๐ค๐ฃ๐จ ๐๐ค๐ง ๐ฅ๐๐ฉ๐๐๐ฃ๐ฉ๐จ ๐ฌ๐๐ค ๐๐ง๐ ๐๐๐ค๐ก๐ค๐๐๐ ๐ฃ๐รฏ๐ซ๐ ๐ซ๐๐ง๐จ๐ช๐จ ๐๐๐ค ๐๐ญ๐ฅ๐๐ง๐๐๐ฃ๐๐๐? ๐ขWhat ๐๐จ๐๐ฌ #TYK-2 #inhibition mean for ๐ญ๐ก๐ #๐ฉ๐ฌ๐จ๐ซ๐ข๐๐ฌ๐ข๐ฌ ๐ฉ๐๐ญ๐ข๐๐ง๐ญ treatment landscape? ๐ขAnd when do I recommend an i๐ง๐ฃ๐๐๐ญ๐๐๐ฅ๐ ๐ฏ๐๐ซ๐ฌ๐ฎ๐ฌ ๐จ๐ซ๐๐ฅ therapy ๐๐จ๐ซ ๐ฆ๐ฒ ๐ฉ๐๐ญ๐ข๐๐ง๐ญ? ๐ซ ๐ง๐ต๐ถ๐ ๐บ๐ฎ๐ฟ๐ธ๐ ๐ฎ ๐ณ๐ถ๐ฟ๐๐ ๐ณ๐ผ๐ฟ ๐๐ต๐ฒ ๐ฆ๐ธ๐ถ๐ป ๐ฎ๐ป๐ฑ ๐๐ผ๐ถ๐ป๐๐ ๐ฃ๐ผ๐ฑ๐ฐ๐ฎ๐๐- ๐๐ฒ ๐ต๐ฎ๐๐ฒ ๐๐๐ผ ๐ด๐๐ฒ๐๐ ๐ฒ๐ ๐ฝ๐ฒ๐ฟ๐๐ ๐ผ๐ป ๐๐ต๐ฒ ๐๐ต๐ผ๐ ๐ฎ๐ ๐๐ต๐ฒ ๐๐ฎ๐บ๐ฒ ๐๐ถ๐บ๐ฒ! ๐ช๐ฒ ๐ฎ๐ฟ๐ฒ ๐ด๐ผ๐ถ๐ป๐ด ๐๐ผ ๐น๐ผ๐ผ๐ธ ๐ฎ๐ ๐ง๐ฌ๐๐ฎ ๐ถ๐ป๐ต๐ถ๐ฏ๐ถ๐๐ถ๐ผ๐ป, ๐ฎ๐ป๐ฑ ๐ถ๐โ๐ ๐ฟ๐ผ๐น๐ฒ ๐ถ๐ป ๐๐ต๐ฒ ๐ฝ๐๐ผ๐ฟ๐ถ๐ฎ๐๐ถ๐ ๐๐ฟ๐ฒ๐ฎ๐๐บ๐ฒ๐ป๐ ๐น๐ฎ๐ป๐ฑ๐๐ฐ๐ฎ๐ฝ๐ฒ ๐๐ถ๐๐ต ๐ฎ ๐ณ๐ผ๐ฐ๐๐ ๐ผ๐ป ๐ฎ ๐ป๐ฒ๐ ๐ผ๐ฟ๐ฎ๐น ๐๐ฒ๐น๐ฒ๐ฐ๐๐ถ๐๐ฒ ๐ง๐ฌ๐๐ฎ ๐ถ๐ป๐ต๐ถ๐ฏ๐ถ๐๐ผ๐ฟ ๐ฎ๐ด๐ฒ๐ป๐ ๐ฐ๐ฎ๐น๐น๐ฒ๐ฑ ๐ฑ๐ฒ๐๐ฐ๐ฟ๐ฎ๐๐ฎ๐ฐ๐ถ๐๐ถ๐ป๐ถ๐ฏ ๐ฎ๐ป๐ฑ ๐๐ต๐ฎ๐ ๐๐ต๐ถ๐ ๐๐ฒ๐น๐ฒ๐ฐ๐๐ถ๐๐ฒ๐น๐ ๐ฐ๐ผ๐ป๐ณ๐ฒ๐ฟ๐ ๐ณ๐ฟ๐ผ๐บ ๐ฎ ๐๐ฎ๐ณ๐ฒ๐๐ ๐ฝ๐ฟ๐ผ๐ณ๐ถ๐น๐ฒ. ๐๐ผ๐ฒ๐ ๐ถ๐ ๐ง๐ฌ๐ ๐ฎ๐น๐น ๐๐ต๐ฒ ๐ฏ๐ผ๐ ๐ฒ๐? ๐๐ฒ๐โ๐ ๐ณ๐ถ๐ป๐ฑ ๐ผ๐๐! ๐๏ธ๐๏ธ๐๏ธ ๐๐๐ซ๐ญ II with Dr.Geeta Yadav and Dr.Marissa Joseph! Episode Learning Objectives โโApply current evidence to key efficacy and safety considerations for the oral, selective allosteric tyrosine kinase 2 (TYK2) inhibitor deucravacitinib ย Describe the summary details and potential clinical implications of the pivotal trials POETYK-1 and POETYK-2 Discuss the role of TYK-2 inhibition in moderate to severe psoriasis and the patient journey ABOUT Dr. Marissa Joseph, MSc, MD, FRCPC ( Pediatrics), FRCPC ( Dermatology) โถ๏ธEpisode supported by an IME Grant from Bristol Myers Squibb
๐ก๐ก๐ก ๐๐ซ.๐๐๐๐๐ฏ ๐๐ง๐ ๐๐ซ.๐๐จ๐ฌ๐๐ฉ๐ก ๐ฅ๐จ๐จ๐ค ๐ญ๐จ ๐ฌ๐๐ญ๐ญ๐ฅ๐ ๐ญ๐ก๐ ๐๐๐๐๐ญ๐ ๐ข๐ง ๐๐๐๐ ๐๐ ๐จ๐ ๐ฐ๐ป ๐ป๐จ๐ฒ๐ฌ๐บ 2 ๐ป๐ถ ๐ป๐๐ฒ 2.
๐ข๐๐๐ฏ๐ ๐ฒ๐จ๐ฎ ๐๐๐๐ง ๐ฐ๐จ๐ง๐๐๐ซ๐ข๐ง๐ ๐ฐ๐ก๐๐ญ'๐ฌ ๐ญ๐ก๐ ๐ซ๐๐๐ฅ ๐๐ข๐๐๐๐ซ๐๐ง๐๐ ๐๐๐ญ๐ฐ๐๐๐ง #๐๐๐ ๐ข๐ง๐ก๐ข๐๐ข๐ญ๐ข๐จ๐ง ๐๐ง๐ #๐๐๐-๐ ๐ข๐ง๐ก๐ข๐๐ข๐ญ๐ข๐จ๐ง? ๐๐ซ๐๐ง'๐ญ ๐ญ๐ก๐๐ฒ ๐ฉ๐๐ซ๐ญ ๐จ๐ ๐ญ๐ก๐ ๐ฌ๐๐ฆ๐ ๐ฉ๐๐ญ๐ก๐ฐ๐๐ฒ? ย
๐ช๐ฒ๐น๐น ๐๐ฒ ๐๐ฎ๐ธ๐ฒ ๐ฎ ๐ฑ๐ฒ๐ฒ๐ฝ ๐ฑ๐ถ๐๐ฒ ๐ถ๐ป๐๐ผ ๐๐ต๐ฒ ๐๐ฎ๐ณ๐ฒ๐๐ ๐ฐ๐ผ๐ป๐๐ฒ๐ฟ๐๐ฎ๐๐ถ๐ผ๐ป ๐ฎ๐ป๐ฑ seek clarify for you when it comes to all you need to know about key ๐ง๐ฌ๐ ๐๐ ๐๐๐ ๐๐ถ๐ฑ๐ฒ ๐ฒ๐ณ๐ณ๐ฒ๐ฐ๐ ๐ฎ๐ป๐ฑ ๐บ๐ผ๐ป๐ถ๐๐ผ๐ฟ๐ถ๐ป๐ด ๐ฐ๐ผ๐ป๐๐ถ๐ฑ๐ฒ๐ฟ๐ฎ๐๐ถ๐ผ๐ป๐.
Our experts ๐ฎ๐น๐๐ผ ๐ฏ๐ฟ๐ฒ๐ฎ๐ธ๐ฑ๐ผ๐๐ป ย ๐ฃ๐ข๐๐ง๐ฌ๐-๐ญ ๐ฎ๐ป๐ฑ ๐ฃ๐ข๐๐ง๐ฌ๐-๐ฎ ๐ฎ๐ป๐ฑ ๐๐ต๐ฎ๐ฟ๐ฒ ๐๐ต๐ฒ๐ถ๐ฟ ๐ฐ๐ฎ๐ป๐ฑ๐ถ๐ฑ ๐๐ต๐ผ๐๐ด๐ต๐๐ ๐ผ๐ป ๐๐ต๐ฒ๐ฟ๐ฒ ๐๐ต๐ฒ๐ ๐๐ฒ๐ฒ ๐๐ต๐ฒ ๐ฝ๐น๐ฎ๐ฐ๐ฒ ๐ผ๐ณ ๐ฎ ๐ง๐ฌ๐-๐ฎ ๐ถ๐ป๐ต๐ถ๐ฏ๐ถ๐๐ผ๐ฟ, ๐ถ๐ป ๐๐ต๐ฒ๐ถ๐ฟ ๐ฝ๐ฟ๐ฎ๐ฐ๐๐ถ๐ฐ๐ฒ๐, ๐ณ๐ผ๐ฟ ๐๐ต๐ฒ ๐๐ฟ๐ฒ๐ฎ๐๐บ๐ฒ๐ป๐ ๐ผ๐ณ ๐บ๐ผ๐ฑ๐ฒ๐ฟ๐ฎ๐๐ฒ ๐๐ผ ๐๐ฒ๐๐ฒ๐ฟ๐ฒ ๐ฝ๐๐ผ๐ฟ๐ถ๐ฎ๐๐ถ๐.
๐ข๐ผ๐ง๐ ๐ฉ๐๐๐ง๐ ๐๐ฃ๐ฎ ๐ฅ๐ง๐๐๐ฉ๐๐๐๐ก ๐๐ค๐ฃ๐จ๐๐๐๐ง๐๐ฉ๐๐ค๐ฃ๐จ ๐๐ค๐ง ๐ฅ๐๐ฉ๐๐๐ฃ๐ฉ๐จ ๐ฌ๐๐ค ๐๐ง๐ ย ๐๐๐ค๐ก๐ค๐๐๐ ๐ฃ๐รฏ๐ซ๐ ย ๐ซ๐๐ง๐จ๐ช๐จ ๐๐๐ค ๐๐ญ๐ฅ๐๐ง๐๐๐ฃ๐๐๐?
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๐ขWhat ๐๐จ๐๐ฌ #TYK-2 #inhibition mean for ๐ญ๐ก๐ #๐ฉ๐ฌ๐จ๐ซ๐ข๐๐ฌ๐ข๐ฌ ๐ฉ๐๐ญ๐ข๐๐ง๐ญ treatment landscape?
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๐ขAnd when do I recommend an i๐ง๐ฃ๐๐๐ญ๐๐๐ฅ๐ ๐ฏ๐๐ซ๐ฌ๐ฎ๐ฌ ๐จ๐ซ๐๐ฅ therapy ๐๐จ๐ซ ๐ฆ๐ฒ ๐ฉ๐๐ญ๐ข๐๐ง๐ญ?
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๐ซ ๐ง๐ต๐ถ๐ ๐บ๐ฎ๐ฟ๐ธ๐ ๐ฎ ๐ณ๐ถ๐ฟ๐๐ ๐ณ๐ผ๐ฟ ๐๐ต๐ฒ ๐ฆ๐ธ๐ถ๐ป ๐ฎ๐ป๐ฑ ๐๐ผ๐ถ๐ป๐๐ ๐ฃ๐ผ๐ฑ๐ฐ๐ฎ๐๐- ๐๐ฒ ๐ต๐ฎ๐๐ฒ ๐๐๐ผ ๐ด๐๐ฒ๐๐ ๐ฒ๐ ๐ฝ๐ฒ๐ฟ๐๐ ๐ผ๐ป ๐๐ต๐ฒ ๐๐ต๐ผ๐ ๐ฎ๐ ๐๐ต๐ฒ ๐๐ฎ๐บ๐ฒ ๐๐ถ๐บ๐ฒ!
๐ช๐ฒ ๐ฎ๐ฟ๐ฒ ๐ด๐ผ๐ถ๐ป๐ด ๐๐ผ ๐น๐ผ๐ผ๐ธ ๐ฎ๐ ๐ง๐ฌ๐๐ฎ ๐ถ๐ป๐ต๐ถ๐ฏ๐ถ๐๐ถ๐ผ๐ป, ๐ฎ๐ป๐ฑ ๐ถ๐โ๐ ๐ฟ๐ผ๐น๐ฒ ๐ถ๐ป ๐๐ต๐ฒ ๐ฝ๐๐ผ๐ฟ๐ถ๐ฎ๐๐ถ๐ ๐๐ฟ๐ฒ๐ฎ๐๐บ๐ฒ๐ป๐ ๐น๐ฎ๐ป๐ฑ๐๐ฐ๐ฎ๐ฝ๐ฒ ๐๐ถ๐๐ต ๐ฎ ๐ณ๐ผ๐ฐ๐๐ ๐ผ๐ป ๐ฎ ๐ป๐ฒ๐ ๐ผ๐ฟ๐ฎ๐น ๐๐ฒ๐น๐ฒ๐ฐ๐๐ถ๐๐ฒ ๐ง๐ฌ๐๐ฎ ๐ถ๐ป๐ต๐ถ๐ฏ๐ถ๐๐ผ๐ฟ ๐ฎ๐ด๐ฒ๐ป๐ ๐ฐ๐ฎ๐น๐น๐ฒ๐ฑ ๐ฑ๐ฒ๐๐ฐ๐ฟ๐ฎ๐๐ฎ๐ฐ๐ถ๐๐ถ๐ป๐ถ๐ฏ ๐ฎ๐ป๐ฑ ๐๐ต๐ฎ๐ ๐๐ต๐ถ๐ ๐๐ฒ๐น๐ฒ๐ฐ๐๐ถ๐๐ฒ๐น๐ ๐ฐ๐ผ๐ป๐ณ๐ฒ๐ฟ๐ ๐ณ๐ฟ๐ผ๐บ ๐ฎ ๐๐ฎ๐ณ๐ฒ๐๐ ๐ฝ๐ฟ๐ผ๐ณ๐ถ๐น๐ฒ.
๐๐ผ๐ฒ๐ ๐ถ๐ ๐ง๐ฌ๐ ๐ฎ๐น๐น ๐๐ต๐ฒ ๐ฏ๐ผ๐ ๐ฒ๐? ๐๐ฒ๐โ๐ ๐ณ๐ถ๐ป๐ฑ ๐ผ๐๐!
๐๏ธ๐๏ธ๐๏ธ ๐๐๐ซ๐ญ II with Dr.Geeta Yadav and Dr.Marissa Joseph!
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Episode Learning Objectives
ABOUT Dr. Marissa Joseph, MSc, MD, FRCPC ( Pediatrics), FRCPC ( Dermatology)
Toronto, ON
Dr. Marissa Josephย is a board certified Pediatrician and Dermatologist and completed her Pediatric training at the Hospital For Sick Children, followed by her Dermatology residency at the University of Toronto. She completed a MSc in Community Health at the Dalla Lana School of Public Health.
Dr. Joseph is full time academic faculty at the University of Toronto. She has received and has been nominated for teaching awards in both undergraduate and postgraduate medical education.ย
Dr. Joseph is the Medical Director of the Ricky Kanee Schachter Dermatology Centre at Women's College Hospital. She also works at the Hospital For Sick Children where she manages children with complex dermatologic disease in outpatient and inpatient settings, as well as a pediatric laser treatment program. Dr. Joseph enjoys her diverse practice in general adult, pediatric and surgical dermatology. Her clinical and research interests include inflammatory skin disorders such as psoriasis, atopic dermatitis, and hidradenitis suppurativa; genodermatoses, and equity, diversity and inclusivity.
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ABOUT Dr. Geeta Yadav, MSc, MD, FRCPC ( Pediatrics), FRCPC ( Dermatology)
Toronto, ON
Dr. Geeta Yadav is an expert in both medical and cosmetic dermatology. A second-generation Canadian, her interest in under-serviced communities and treating BIPOC patients was inspired by her childhood travels to India. She holds a masterโs degree in International Health from Johns Hopkins and completed her dermatology training at the University of Toronto, where she still teaches today. Dr. Yadav is a fellow of the Royal College of Physicians and Surgeons, the American Academy of Dermatology, and the European Academy of Dermatology and Venereology.ย
When sheโs not working, she volunteers as an Alumni Governor at the University of Toronto. She also loves running, dancing, and spending time with her husband and three young children.ย
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โถ๏ธEpisode supported by an IME Grant from Bristol Myers Squibb